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Q: Why does a recent guideline recommend against the use of DPP4 inhibitors such as linagliptin (Trajenta®) in people with type 2 diabetes?
A: The answer is in the current edition of PAD Refills. Make sure to subscribe so you don’t miss out on news and updates!
The next phase of the Biosimilars Initiative is focused on patients with plaque psoriasis with PharmaCare coverage for ustekinumab (Stelara®). In the six-month period from May 30 to December 2, 2024, PharmaCare is switching coverage from the originator biologic to a biosimilar option.
Originator | PharmaCare-covered biosimilar | Condition |
---|---|---|
Ustekinumab (Stelara®) | Jamteki™ | Plaque psoriasis (PsO) |
To maintain PharmaCare coverage, patients currently covered for the originator biologic Stelara® must, in consultation with their prescriber, switch to the approved biosimilar product: Jamteki™.
Prescribers can submit HLTH 5849 to request a list of patients for whom they've prescribed ustekinumab.
All new Special Authority (SA) requests, including renewals, for ustekinumab will only be approved for Jamteki. Limited coverage criteria updated.
Patients with PharmaCare coverage for Stelara who wish to maintain ustekinumab coverage must transition to an approved biosimilar product. To maintain patients’ coverage, prescribers must write a new prescription for their patients on Stelara, indicating the transition to a specific biosimilar. Pharmacists are essential to identifying and informing patients who need a new prescription.
For patients with existing ustekinumab SA approval, eligible biosimilar brands will be covered. Prescribers do not need to submit a new SA request for coverage of the biosimilar until the next SA renewal date.
Stelara becomes a PharmaCare non-benefit (not covered). Only the approved biosimilar products are authorized for continued ustekinumab coverage.
Special Authority requests for patients who are unable to transition to biosimilars will be considered on an exceptional case-by-case basis.
Although pharmacists cannot adapt a prescription for an originator drug to a biosimilar, they can help identify and notify patients, and letting them know they need a new prescription, who may be affected by the switch. In recognition of this support to patients, a $15 per patient support fee is offered to pharmacies for their efforts. The fee is submitted as a PIN (66128474) in PharmaNet, to be paid monthly, in accordance with the monthly payment schedule.
During interactions with a patient, if a pharmacist notices that a patient’s medication record indicates current use of Stelara, they should:
Only one patient support fee can be claimed per PHN. Support fees must be submitted within the switch period window. As key points of contact for patients, pharmacists play a valuable role in bringing positive awareness to the Initiative. Patients frequently turn to pharmacists as a source of health information and rely on those conversations to inform discussions with their prescribers.
A patient support fee is also available to prescribers. For more information, visit Biosimilars Initiative for health professionals
Resources
PharmaCare is seeing a number of claims related to prescriptions that name non-prescribers as the prescriber. The issue if often due to a user error, where a pharmacist enters the wrong Ref ID, or selects the wrong name for the prescriber in PharmaNet. Some providers share the same name, or have multiple Ref IDs in PharmaNet – some are prescribers, some are not.
Non-prescribers, such as licensed practical nurses or registered pharmacy technicians, do not have the authority to prescribe medications and should not be recorded as the prescriber in any circumstance. If a prescription is received from a non-prescriber, pharmacists should contact the medical site that is the source of the prescription, to confirm who the correct prescriber should be.
Non-prescribers are indicated in PharmaNet by the following non-prescriber codes: L9, NX, RX, YX, T9.
Non-prescribers include:
PharmaCare Audit’s timeframe between the removal and return of prescription records has increased from 5 to 20 business days to align with other pharmacy records.
Audits are performed to ensure that PharmaCare providers, and claims for drugs, medical supplies, and services paid by PharmaCare to a provider, comply with the terms of relevant Acts, regulations, bylaws, policies and procedures.
When auditors remove records from a provider site, they must return those records within 20 business days. Previously, prescription records were returned within 5 business days, however, going forward all documentation removed from a provider will fall under the same 20-day timeframe.
Auditors typically review prescription records that are at least four months old. Since the information from these prescription records have already been entered into pharmacy software, and the paper prescription records are no longer being actively used, the new 20-business-day turnaround should not affect pharmacy operations. PharmaCare Audit will continue to try and limit the amount of time they possess any provider’s records and return them as soon as they can.
Refer to the PharmaCare Policy Manual, section 10.1 – Audit to learn more about PharmaCare’s audit process and policy.
Resources
As of May 8, 2024, the PharmaCare Prosthetic and Orthotic Policy Manual has been updated for clarity.
This update changed the term “basic functionality” to “basic function” and ensures that this term is only used to describe the level of function that a device offers. The term “activities of daily living (ADL)” was introduced to refer to clients’ functional abilities, as they inform the level of device function that may be eligible for PharmaCare coverage.
The language updates did not alter any existing PharmaCare policies.
Resources
June 1 marks the 1-year anniversary of pharmacists prescribing in B.C. and PharmaCare’s Minor Ailments and Contraception Service (MACS) program. Pharmacists in B.C. can assess people for 21 minor ailments and contraception and can prescribe medications for these when appropriate. PharmaCare providers submit claims for reimbursement through the MACS program.
Within three months of the program’s launch, more than 75,500 patients received a MACS service; over 3,500 pharmacists (about 67%* of pharmacists in B.C.) provided MACS. The numbers of participating pharmacists and patients served have continued to rise steadily. Data inclusive of April 30, 2024, indicates that the number of patients who have received MACS has grown to over 280,000. Approximately 77%* of pharmacists have now provided MACS.
The most assessed conditions throughout the program’s history has been for uncomplicated urinary tract infections (UTIs) and contraception, each amounting to 20% of all MACS assessments from June until April 30, 2024. In 89% of these cases, patients were prescribed medication for treatment, with the antibiotic nitrofurantoin being the most prescribed drug.
The Ministry developed a program evaluation plan to assess the impact of pharmacists prescribing for minor ailments and contraception (PPMAC) on patients, health providers and the health system. Evaluation activities are underway to assess the uptake and effect of the initiative, and identify areas where quality of care can be improved. These include:
Ongoing evaluation will allow PharmaCare to understand how to support pharmacies as they help B.C. residents meet even more of their health care needs in a timely way—right in the pharmacy. Refer to PPMAC evaluation framework (PDF, 97KB) for an overview of the evaluation plan.
PharmaCare welcomes feedback from pharmacies about their experiences providing MACS and factors that have been barriers to their participation. Email us at MACS@gov.bc.ca
For more information on MACS, including instructions on how to begin providing MACS to your community, visit the government’s MACS web page.
All pharmacies are encouraged to print off and post the pharmacist services poster below.
Interior Health has produced a poster for pharmacies in their region. Print it and post it!
Island Health has produced posters and rack cards for pharmacies. Print them and post them!
Resources
*Number refers to MACS provided by “active” pharmacists who have submitted at least one claim
On May 30, UBC Continuing Pharmacy Professional Development (CPPD) released the following free, accredited programs to support the Minor Ailments and Contraception Service (MACS):
Pharmacists are encouraged to enrol in these programs and continue to seek other educational opportunities and resources to support their participation in MACS.
Other educational opportunities available through UBC CPPD: Continuing Pharmacy Professional Development Programs and Building Cultural Safety and Humility for First Nations Clients into Pharmacy Practice.
The Precision Medicine and Genetic Services unit at the Ministry of Health is running a survey to better understand the experiences and requirements of pharmacogenomics (PGx) education and awareness among health care providers. The survey will serve as a foundation for an upcoming education and awareness campaign. Visit Pharmacogenomics (PGx) Survey to take the survey. The survey is open until June 30, 2024.
PGx is a field of research that studies how a person's genetic makeup affects their response to medication. PGx testing provides information that can help identify drugs and doses that are most likely to work for an individual patient.
Resources
The Therapeutics Initiative (TI) recently published a letter that provides guidance on antibiotic use in dental infections and reviews the harms of clindamycin. Visit Therapeutics initiative [148] to read the letter.
Resources
Pharmacies will continue to be paid $75 per case of COVID-19 rapid antigen tests (RAT) kits distributed, regardless of the number of kits in a case; as of May 29, 2024, Artron cases contain 115 kits, down from 140.
Community pharmacies may claim a fee for distributing, at no charge to clients, publicly funded COVID-19 RAT tests, along with plain language instruction sheets. They may also provide a QR code that links to the instruction sheet if the client prefers.
Pharmacy staff must enter the PIN in PharmaNet on opening a case. RAT kits must be distributed, one at a time, at no charge, to anyone 18 and over. Each kit contains 5 tests.
As previously communicated, Health Canada approved a 6-month extension to the expiry date printed on the case.
For details about shelf-life extensions, visit:
For claims procedures and further details, visit:
Resources
Plain language RAT kit instructions: English | ASL | Arabic | Simplified Chinese | Traditional Chinese | Farsi | French | Korean | Punjabi | Spanish | Vietnamese | Tigrinya | Russian | Ukrainian
Since the last newsletter, PharmaCare has paid pharmacies for COVID-19 rapid antigen test (RAT) kit distribution as follows:
Payment month | Payment date |
---|---|
March 2024 | June 3, 2024 |
PharmaCare has added the following regular benefit coverage items to the PharmaCare drug list.
Drug name | estradiol vaginal inserts (Imvexxy™) | ||
---|---|---|---|
Date effective | May 14, 2024 | ||
Indication |
For the treatment of postmenopausal moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy. |
||
DINs | 02503689 02503697 |
Strength & form | 4 mcg 10 mcg |
Drug name | budesonide rectal foam (Uceris™) | ||
---|---|---|---|
Date effective | June 18, 2024 | ||
Indication |
For the induction of remission in adult patients with active mild to moderate distal ulcerative colitis. |
||
DINs | 02498057 | Strength & form | 2 mg/actuation |
Special notes | When submitting to PharmaCare, please bill per actuation. |
PharmaCare has added the following Limited Coverage items to the PharmaCare drug list. Special Authority approval is required for coverage.
Drug name | filgrastim (Nypozi®) | ||
---|---|---|---|
Date effective | May 14, 2024 | ||
Indication |
For the prevention and treatment of febrile neutropenia |
||
DINs | 02520990 02521008 |
Strength & form | 300 mcg/0.5 mL pre-filled syringe 480 mcg/0.8 mL pre-filled syringe |
Drug name | risankizumab (Skyrizi®) | ||
---|---|---|---|
Date effective | May 30, 2024 | ||
Indication |
For the treatment of adult patients with moderately to severely active Crohn’s disease |
||
DINs | 02532107 02532093 |
Strength & form | 600 mg/10 mL vial 360 mg/2.4 mL prefilled cartridge with on-body injector |
Drug name | ustekinumab biosimilar (Jamteki™) | ||
---|---|---|---|
Date effective | May 30, 2024 | ||
Indication |
For the treatment of chronic moderate to severe plaque psoriasis in adult patients |
||
DINs |
02543036 |
Strength & form |
45 mg/0.5 mL pre-filled syringe |
Drug name | nirmatrelvir/ritonavir (Paxlovid ™) | ||
---|---|---|---|
Date effective | May 28, 2024 | ||
Indication | To reduce the risk of hospitalization in adults with mild to moderate COVID-19 at high risk of progressing to severe COVID-19 | ||
DINs | 02524031 02527804 |
Strength & form | 150 mg of nirmatrelvir and 100 mg of ritonavir tablets |
The knowledge and experience of patients, caregivers and patient groups is integral to B.C.’s drug review process. If you know someone who’s taking one of the drugs below or who has a condition any of the drugs treats, please encourage them to visit www.gov.bc.ca/BCyourvoice.
Your Voice is now accepting input on the following drugs:
Drug | Indication | Input window |
---|---|---|
fidaxomicin (Dificid®) | For first-line treatment of Clostridium difficile infection in adults 18 years of age and older. | May 29 to June 25 at 11:59 pm |
remdesivir (Veklury®) | For COVID-19 in non-hospitalized adult and pediatric patients at least 12 years of age, weighing at least 40 kg, who are at high risk for progression to severe COVID-19. | May 29 to June 25 at 11:59 pm |
etrasimod (Velsipity™) | For moderately to severely active ulcerative colitis (UC) in adult patients. | May 29 to June 25 at 11:59 pm |
tofacitinib (generics) | For the treatment of adult patients with active ankylosing spondylitis (AS). | June 12 to July 9 at 11:59 pm |
tofacitinib (generics) | For the treatment of adult patients with active psoriatic arthritis (PsA). | June 12 to July 9 at 11:59 pm |
The Ministry of Health is deeply concerned about recent reports that some British Columbia pharmacies are providing cash to people for using their pharmacy, including to receive opioid use disorder treatment.
Offering incentives to beneficiaries to use a pharmacy service – including in relation to dispensing prescriptions and witnessing methadone ingestion – is strictly prohibited. This includes offering money, gifts, discounts, rebates, refunds, customer loyalty schemes, coupons, and goods or rewards. Among other concerns, pharmacy incentives may negatively influence a patient’s treatment choice.
It is an offence under section 51 of the Pharmaceutical Services Act (PSA) to offer an incentive as an inducement for a beneficiary to receive a benefit from a particular provider. A person who commits such an offence is liable on conviction to a fine of up to $200,000 and/or 6 months imprisonment. Additionally, evidence that a pharmacy is providing incentives may result in administrative fines (up to $50,000) and cancellation of the pharmacy’s enrolment in PharmaCare.
The Ministry’s special investigations unit and PharmaCare audit teams are conducting investigations or audits in relation to compliance with the Act, which include on-site visits.
All PharmaCare providers must fully comply with the Act and its regulations – including in relation to incentives. If you know or have reason to believe that other pharmacies are not complying with the Act (including by offering incentives), please contact Incentives@gov.bc.ca.
References
As of May 28, 2024, PharmaCare has listed Paxlovid under Plan Z to replace the federal government supply which ended in March 2024. Plan Z (Assurance) will provide full coverage of Paxlovid for BC residents with active Medical Services Plan (MSP) coverage. Exceptional Plan Z coverage (e.g., patients who live outside of BC or Canada) for Paxlovid will no longer be available.
As the federal government supply is no longer provided, pharmacies are to obtain Paxlovid supplies from their wholesaler.
Pharmacists and prescribers are reminded that Paxlovid is only beneficial to patients considered at higher risk of progressing to serious illness, such as those who are severely immunosuppressed.
The Ministry of Health has added prescribing guidance to the Paxlovid prescription eForm that prescribers are strongly encouraged to use.
DIN | Generic name | Brand name | Dosage form | Maximum PharmaCare covers |
---|---|---|---|---|
02524031 | nirmatrelvir/ritonavir | Paxlovid | 150 mg of nirmatrelvir and 100 mg of ritonavir tablets | $1391.99/package |
02527804 | nirmatrelvir/ritonavir | Paxlovid | 150 mg of nirmatrelvir and 100 mg of ritonavir tablets | $1391.99/package |
PharmaCare continually reviews its coverage policies for the products it covers. Any change to coverage for Paxlovid, or any other PharmaCare benefit, will be communicated to pharmacists, prescribers and patients in advance.
Resources
PharmaCare newsletters are published on the first Tuesday of each month, with special releases sometimes published mid-month. Newsletters communicate drug listings, PharmaCare and PharmaNet policy updates, and other pertinent information for PharmaCare providers and other B.C. health professionals.
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The PharmaCare Newsletter team works from the territory of the Lekwungen People, including the Songhees and Esquimalt Nations. Our gratitude extends to them, and all the Indigenous Peoples on whose territories and lands we build relationships.
Search past newsletters on the Newsletter search page.
BC PharmaCare counts on pharmacy and device providers to practise cultural safety and humility.
To learn more, read Coming Together for Wellness, a series of articles by First Nations Health Authority (FNHA) and PharmaCare, and consider taking the online San’yas Indigenous Cultural Safety course.
Active advisories:
Dextroamphetamine SR capsules; Cholestyramine, colestipol and colesevelam; Tamsulosin capsules and tablets; Prazosin tablets, Sabril® tablets; nitroglycerin sprays & tablets; pediatric antibiotic suspensions; Glucagon for injection.
Visit Drug shortages for full list and details.