Limited coverage criteria – filgrastim

Last updated on March 19, 2025

 

Return to the Special Authority drug list

Generic name

filgrastim

Brand name

Strength

Form

Grastofil® 300 mcg/0.5 mL 
480 mcg/0.8 mL
pre-filled syringe
Nivestym® 300 mcg/0.5 mL 
480 mcg/0.8 mL

pre-filled syringe

300 mcg/1 mL
480 mcg/1.6 mL
single-use vial
Nypozi® 300 mcg/0.5 mL
480 mcg/0.8 mL
pre-filled syringe

Special Authority criteria

Approval period

For primary prophylaxis of febrile neutropenia in cancer patients receiving potentially curative myelosuppressive chemotherapy regimens where the risk of febrile neutropenia is ≥ 20%

6 months

For secondary prophylaxis of febrile neutropenia in cancer patients receiving potentially curative myelosuppressive chemotherapy 6 months
For the rescue of prolonged febrile neutropenia following chemotherapy 6 months
For cancer patients undergoing peripheral blood progenitor cell collection and therapy 6 months
For post–bone marrow transplant patients to stimulate bone marrow engraftment (start greater than or equal to d+1) 6 months
For post–bone marrow transplant patients requiring rescue of failure to engraft (start greater than or equal to d+14) 6 months

For patients with the following benign disorders:

  • Chronic benign cyclical neutropenia
    OR
  • Myelodysplastic disorders or aplastic anemia, while the patient awaits bone marrow transplantation
6 months

Practitioner exemptions

  • None

Special notes

  • For coverage for HIV-infected patients, please contact BC Centre for Excellence in HIV/AIDS

Special Authority request form(s)